# Nanotechnology / Engineering at the atomic scale

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Category: Technology
Slides: 13
Updated: 2026-05-17T20:55:45.972Z
Tags: catalog, tech, nanotech

## Summary

Caltech, December 29, 1959 . Richard Feynman delivers the founding lecture of nanotechnology before the field exists. Key sections include: NANO TECH / NOLOGY; "Plenty of Room at the Bottom"; One nanometer is vanishingly small.; Scanning Tunneling Microscope / 1981; "IBM" in xenon atoms / 1989; A rolled sheet of graphene / 1991; One atom thick / 2004; Chemistry does the building for you.; Where nano already ships.; Patterning silicon at the atom limit..

## Slide Outline

1. NANO TECH / NOLOGY
2. "Plenty of Room at the Bottom"
3. One nanometer is vanishingly small.
4. Scanning Tunneling Microscope / 1981
5. "IBM" in xenon atoms / 1989
6. A rolled sheet of graphene / 1991
7. One atom thick / 2004
8. Chemistry does the building for you.
9. Where nano already ships.
10. Patterning silicon at the atom limit.
11. Toxicology hasn't caught up.
12. What nano is , and isn't.
13. Where to go next.

## Slide Transcript

### Slide 1: NANOTECH
/NOLOGY

- // 01 &middot; INTRODUCTION
- Engineering at the atomic scale.
- 10-9 meter
- ~10 atoms across
- since 1959

### Slide 2: "Plenty of Room
at the Bottom"

- // 02 &middot; ORIGINS
- Caltech, December 29, 1959. Richard Feynman delivers the founding lecture of nanotechnology before the field exists.
- "The principles of physics, as far as I can see, do not speak against the possibility of maneuvering things atom by atom."
- &mdash; R. Feynman, APS lecture, 1959

### Slide 3: One nanometer is vanishingly small.

- // 03 &middot; THE SCALE
- 1 nm = 1 / 1,000,000,000 of a meter. About ~10 atoms laid side by side. A human hair is roughly 80,000 nm wide.
- 1 m
- human
- 1 mm
- grain of sand &mdash; 10-3
- 1 &micro;m
- bacterium &mdash; 10-6
- 100 nm
- virus &mdash; 10-7
- 2 nm
- DNA double helix
- 0.1 nm
- hydrogen atom &mdash; 10-10

### Slide 4: Scanning Tunneling
Microscope / 1981

- // 04 &middot; SEEING ATOMS
- A sharp metal tip hovers a few atomic diameters above a surface. Quantum tunneling current resolves individual atoms.
- Invented by Gerd Binnig and Heinrich Rohrer at IBM Z&uuml;rich
- Nobel Prize in Physics, 1986
- Resolution: lateral ~0.1 nm, vertical ~0.01 nm
- The first instrument to see &mdash; and later move &mdash; single atoms

### Slide 5: "IBM" in xenon
atoms / 1989

- // 05 &middot; MOVING ATOMS
- Don Eigler and Erhard Schweizer at IBM Almaden positioned 35 xenon atoms on a nickel surface to spell their employer's logo.
- Feynman's 1959 conjecture, demonstrated. The image circled the world. From that point on the atomic scale was not just visible &mdash; it was writable.

### Slide 6: A rolled sheet of
graphene / 1991

- // 06 &middot; CARBON NANOTUBES
- Sumio Iijima reports multi-walled carbon nanotubes at NEC. Diameter ~1&ndash;100 nm, length up to centimeters.
- Tensile strength ~100&times; steel at 1/6 the density
- Electrical conductivity rivaling copper
- Thermal conductivity rivaling diamond
- Either metallic or semiconducting depending on chirality

### Slide 7: One atom thick / 2004

- // 07 &middot; GRAPHENE
- Andre Geim and Konstantin Novoselov isolate graphene from graphite using adhesive tape at the University of Manchester.
- Two-dimensional honeycomb lattice of carbon atoms
- Charge mobility ~200,000 cm&sup2;/Vs
- ~200&times; stronger than steel by weight
- Nobel Prize in Physics, 2010

### Slide 8: Chemistry does the
building for you.

- // 08 &middot; SELF-ASSEMBLY
- Push molecules into the right environment and they organize themselves &mdash; driven by hydrogen bonding, van der Waals forces, hydrophobic effects.
- DNA origami: a long strand folded by short staples into shapes (Rothemund, 2006)
- Block copolymers: phase separation creates regular nanostructures
- Lipid bilayers: the same self-assembly that built the first cells
- Bottom-up complement to top-down lithography

### Slide 9: Where nano already ships.

- // 09 &middot; APPLICATIONS
- Most of the field's payoff so far is materials science, not tiny robots. The applications are real and quietly pervasive.
- drug delivery
- lipid nanoparticles for mRNA vaccines
- catalysis
- platinum NPs in fuel cells & converters
- sensors
- CNT & graphene FETs detect single molecules
- batteries
- silicon NPs & nano-coatings boost capacity
- displays
- quantum-dot LEDs (QLED) tune color by size
- coatings
- self-cleaning, anti-reflective, anti-microbial

### Slide 10: Patterning silicon
at the atom limit.

- // 10 &middot; LITHOGRAPHY
- The most economically important nanotech: photolithography on silicon. Each generation shrinks the feature size.
- Deep UV (193 nm): printed nodes from 130 nm down to 7 nm via multi-patterning
- EUV (13.5 nm): ASML's twin-lasered tin-droplet light source &mdash; the only commercial path below 7 nm
- Current leading nodes: ~3 nm (TSMC, Samsung), with 2 nm in pilot
- "Nodes" are marketing &mdash; physical gate pitches are larger, but transistors are nano-scale features

### Slide 11: Toxicology hasn't
caught up.

- // 11 &middot; RISK
- A particle small enough to engineer is small enough to cross membranes you don't want it to cross.
- Nanoparticles can enter cells, cross blood-brain & placental barriers, accumulate in lungs
- Engineered TiO&#8322;, silver, and CNTs raise occupational-exposure concerns
- Environmental persistence: many nanomaterials are designed not to degrade
- Regulation lags &mdash; "nano" rarely appears on ingredient labels

### Slide 12: What nano is, and isn't.

- // 12 &middot; THE HONEST ASSESSMENT
- DELIVERED
- Stronger composites & coatings
- Better catalysts & sensors
- Quantum dots in TVs & displays
- Lipid NPs that delivered the COVID vaccines
- Three decades of Moore's-Law lithography
- DISTANT
- Drexler-style "molecular assemblers"
- Programmable diamondoid mechanosynthesis
- Self-replicating nanobots
- Cell-by-cell medical repair machines
- The science fiction of "molecular nanotechnology" has not arrived. The materials science it inspired quietly powers your phone, your battery, and your vaccine.

### Slide 13: Where to go next.

- // 13 &middot; FURTHER READING
- REFERENCES
- Feynman, R. — "There's Plenty of Room at the Bottom", APS, 1959
- Binnig & Rohrer — Helvetica Physica Acta, 1982 (STM)
- Eigler & Schweizer — Nature 344, 524 (1990)
- Iijima, S. — Nature 354, 56 (1991) (CNTs)
- Novoselov & Geim et al. — Science 306, 666 (2004) (graphene)
- Rothemund, P.W.K. — Nature 440, 297 (2006) (DNA origami)
- Drexler, K.E. — Engines of Creation, 1986
- VIDEO
- Feynman / Plenty of Room &rarr;
- Graphene / Nobel Prize &rarr;
- // END OF DECK &mdash; thank you


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