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Aging — The Mechanics of Getting Older

Average life expectancy in 1900 hovered around the mid-40s. Today it sits near 79 in high-income countries — but the gain came mostly from preventing...

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Average life expectancy in 1900 hovered around the mid-40s. Today it sits near 79 in high-income countries — but the gain came mostly from preventing infants and young adults from dying, not from extending old age. Key sections include: AGING / The mechanics of getting older; We almost doubled the human lifespan in a century.; The Hayflick limit, 1961.; The hallmarks of aging.; Genomic instability.; Telomere attrition.; Epigenetic alterations.; Mitochondrial dysfunction.; Cellular senescence — the zombie cells.; Stem cell exhaustion..

cataloghealthaging
Slide outline
  1. 01AGING / The mechanics of getting older
  2. 02We almost doubled the human lifespan in a century.
  3. 03The Hayflick limit, 1961.
  4. 04The hallmarks of aging.
  5. 05Genomic instability.
  6. 06Telomere attrition.
  7. 07Epigenetic alterations.
  8. 08Mitochondrial dysfunction.
  9. 09Cellular senescence — the zombie cells.
  10. 10Stem cell exhaustion.
  11. 11The blue-zones critique.
  12. 12Plausible interventions, ranked by evidence.
  13. 13References & further viewing.
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https://shipslides.com/d/catalog-health-aging
Category
Health
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41.5 KB
Updated
2026-05-15
LLM text
https://shipslides.com/d/catalog-health-aging/llms.txt
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