About this deck
A clinical-trial style tour of the hallmarks of aging, the interventions actually being tested in humans, and the honest limits of what biology will allow. Key sections include: LONGEVITY / What we know about extending healthspan; From 30 to 80 in a century — and almost none of it from anti-aging.; Lifespan vs healthspan . The goal isn't more years. It's more good years.; The Hallmarks of Aging López-Otín et al., 2013 · updated 2023; Caloric restriction moderate evidence; mTOR & rapamycin moderate evidence; Senolytics early human; Yamanaka factors preclinical Resetting the epigenetic clock; Metformin — the boring candidate moderate evidence; Exercise strongest evidence The intervention with no equal in 2026..
